1 Although the incidence rates in Africa are the lowest in the world, its mortality rates are highest, reflecting the poorer survival outcomes. In conclusion, downstaging breast cancer at diagnosis and improving access to quality care could be pivotal in improving breast cancer survival outcomes in Africa.īreast cancer is the leading cause of cancer morbidity and the second most important cause of mortality from cancer in sub‐Saharan Africa (SSA). Age at diagnosis was not independently associated with increased mortality risk after adjusting for the effect of stage and country‐level HDI. Patients diagnosed at early stages had a 3‐year RS of 78% (71.6–83.3) in contrast to 40.3% (34.9–45.7) at advanced stages (III and IV). The RS varied by registry, ranging from 21.6%(8.2–39.8) at Year 3 in Bulawayo to 84.5% (70.6–93.5) in Namibia. Among patients with known stage, 64.9% were diagnosed in late stages, with 18.4% being metastatic at diagnosis. We equally estimated the excess hazards adjusting for potential confounders. The 1‐, 3‐ and 5‐year observed and relative survival (RS) were estimated by registry, stage and country‐level HDI. Of these, 2,311 were included for survival analyses. We obtained data on a random sample of 2,588 breast cancer incident cases, diagnosed in 2008–2015 from 14 population‐based cancer registries in 12 countries (Benin, Cote d'Ivoire, Ethiopia, Kenya, Mali, Mauritius, Mozambique, Namibia, Seychelles, South Africa, Uganda and Zimbabwe) through the African Cancer Registry Network. Here, we estimate breast cancer survival within SSA by area, stage and country‐level human development index (HDI). Yet, there are few population‐level survival data from Africa and none on the survival differences by stage at diagnosis. Breast cancer is the leading cancer diagnosis and second most common cause of cancer deaths in sub‐Saharan Africa (SSA).
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